Liso Clinic, located in Hatchobori, Chuo Ward, Tokyo, is an orthopedic clinic specializing in the treatment of knee pain and functional impairment. The clinic's most distinctive feature is its integrated approach as a "Specialized Knee Clinic," combining multiple specialized departments including regenerative medicine, orthopedic surgery, physical therapy, and acupuncture under one roof. The clinic addresses a wide range of knee-related symptoms and conditions, including knee osteoarthritis, meniscus injuries, anterior cruciate ligament (ACL) injuries, patellofemoral syndrome, osteochondritis dissecans, medial collateral ligament (MCL) injuries, patellar dislocation, and knee rheumatism, with personalized treatment plans tailored to each patient's condition. Notably, stem cell-based regenerative medicine has gained attention as an option for patients wishing to avoid surgery, with documented cases showing cartilage regeneration. English-speaking services are available, providing reassurance for patients whose native language is not Japanese. Clinic hours are 10:00 AM to 6:00 PM (until 1:00 PM on Saturdays), with closures on Thursdays, Fridays, Sundays, and public holidays. It is known as a facility offering specialized, comprehensive care for those suffering from knee conditions.