Makino Clinic is a psychiatric clinic located in Higashinakano, Nakano Ward, Tokyo. Consultations are held on Wednesdays and Thursdays from 1:30 PM to 6:30 PM, and the clinic also operates on the 2nd and 4th Saturdays of each month. The clinic provides English-speaking services and offers facilities including parking and barrier-free accessibility. The official website notes that physical discomfort with unknown causes may stem from psychological factors, and many patients visit at the recommendation of others even without self-aware symptoms. Common symptoms include irritability, palpitations or chest discomfort, tension or depressed mood, increased fatigue, sensation of a lump in the throat, difficulty sleeping, and poor morning mood. The clinic is closed on Sundays, holidays, and year-end/new-year periods (January 1-3 and December 30-31).