Ai Internal Medicine Clinic is conveniently located on the second floor of CoCoLo Medical Healthy Mall near Nagaoka Station. Opened in 2007, this clinic is staffed by a director certified as a specialist by the Japanese Society of Internal Medicine, the Japanese Society of Nephrology, and the Japanese Society for Dialysis Therapy, who treats lifestyle diseases including hypertension, diabetes, hyperuricemia, kidney disease, and collagen diseases. Clinic hours are Monday through Friday from 8:00 AM to 12:00 PM and 3:00 PM to 6:00 PM, and Saturdays from 8:00 AM to 12:00 PM. The clinic is closed on Wednesday afternoons, Saturday afternoons, Sundays, and holidays. The clinic offers influenza and COVID-19 vaccinations, with both Pfizer and Takeda vaccines available. Appointments can be made online or via email, and a same-day queue reservation system allows patients to check estimated wait times. In addition to Nagaoka Station parking, patients can use the East Exit Hotel Mets parking lot and CoCoLo Nagaoka parking. The clinic also provides English-language services, electronic payment options, and barrier-free accessibility.